Bioanalytics and Integrative Bioengineering Laboratory (Guigen Zhang)The lab focuses on biomedical research in areas including biosensor development, in-situ biomarker detection, integrated understanding of mechanical integrity of bone structures influenced by mechanical environment and oxygen/nutrient transport, characterization of tissues and implant devices, and computational bioengineering.
Biomaterials and Regenerative Medicine Lab (Dr. Ni Su)
At the Biomaterials and Regenerative Medicine Lab, we harness the power of the immune system and biomaterials to advance therapies for various diseases. Nearly every known pathology—from tissue injury and cancer to aging—is influenced by immune function. Our research focuses on engineering biomaterials that can modulate immune responses to promote healing and restore tissue function. We employ cutting-edge biomaterial platforms to construct complex, humanized in vitro disease models for mechanistic discovery and high-throughput drug screening. In parallel, we design biomaterials with tunable biophysical and biochemical cues to directly modulate immune activity and promote tissue regeneration. By integrating principles of immunology, materials science, and stem cell biology, we aim to uncover the underlying mechanisms of immune dysfunction and leverage this knowledge to develop next-generation immunotherapies.
Bio-Photonics Laboratory (Guoqiang Yu)This laboratory develops optical spectroscopy/tomography for in-vivo measurements of blood flow, oxygenation and oxygen metabolism in normal and diseased tissues of animals and humans. The motivation is to explore the feasibility of optical instruments for the diagnosis of various diseases and longitudinal monitoring of therapies. The goal is to create a strong bio-photonics research and teaching program, which vertically integrates physics, optics, engineering and clinical applications.
Bone Quality Laboratory (David Pienkowski)Mechanical testing of hard and soft tissues are the primary focus of this laboratory, two Instron servo-hydraulic mechanical testing systems provide compression, tension, bending and torsional testing capabilities of hard and soft tissue and a variety of prosthetic devices.
Cardiac Rhythm Laboratory (Abhijit Patwardhan)The focus of research conducted in the rhythm dynamics laboratory is on the use of linear and non-linear systems and signal analysis techniques to investigate the dynamics of cardiovascular function.
Nanomedicine Laboratory (Sheng Tong)The Nanomedicine Laboratory at the University of Kentucky is dedicated to the development of cutting-edge technologies for disease treatment. Our research falls into the broad fields of nanobiotechnology, immunoengineering, genome editing, and cancer therapy.
Neural Systems Laboratory (Sridhar Sunderam)This lab focuses on the diagnosis of brain states using physiological measurements, modeling and signal analysis for applications in epilepsy therapy, sleep monitoring, neuroprosthetics and cognitive science. For more information, see the lab page.
Spectroscopic Imaging Laboratory (Caigang Zhu)The Lab is motivated by multidisciplinary applications of novel optical techniques in cancer research. The central focus of the group’s research is to develop optical imaging tools including spectroscopy, microscopy, and spectral imaging platforms for biomedical applications related to tumor metabolism, hypoxia and angiogenesis. The research interests of this Lab include but not limited to vascular and metabolic imaging/spectroscopic techniques for cancer biology and radiation biology study.
